• Tomoki Ishibashi
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    Tomoki Ishibashi, Ph.D.

    Tomoki Ishibashi, Ph.D.

    SPDR at RIKEN, expert in developmental biology, cell biology, molecular biology, and bioinformatics.

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    Research Interest

    I am interested in Development.

    Left-right asymmetric morphogenesis

    • I am elucidating mechanism by which the cell chirality emerges left-right asymmetric morphogenesis at the multi-cellular level by using cultured cell.
    • I had studied about LR-asymmetric development by using Drosphila embryo.

    Left-right asymmetry in *Drosophila*

    • E and ID proteins regulate cell chirality and left–right asymmetric development in Drosophila
    • Statistical Validation Verifies That Enantiomorphic States of Chiral Cells Are Determinant Dictating the Left- or Right-Handed Direction of the Hindgut Rotation in Drosophila
    • Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin
    • extra macrochaetae, encoding Drosophila Id, controls apical cell shape in the hindgut epithelium
    • Chiral cell sliding drives left-right asymmetric organ twisting
    • Cells with Broken Left–Right Symmetry: Roles of Intrinsic Cell Chirality in Left–Right Asymmetric Epithelial Morphogenesis
    • The Drosophila AWP1 ortholog Doctor No regulates JAK/STAT signaling for left-right asymmetry in the gut by promoting receptor endocytosis

    Post-embryonic development, caste differentiation, in termite

    Termites

    I had studied about the molecular mechanism of the caste differentiation by using termites. Importantly, this is the developmental biology of the Superorganism.

    • Plastic brain structure changes associated with the division of labour and ageing in termites
    • A non-invasive method for sexing first and second instar larvae of termites using external morphology
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