I am interested in Development.

Left-right asymmetric morphogenesis

• I am elucidating mechanisms by which the cell chirality emerges left-right asymmetric morphogenesis at the multi-cellular level by using cultured cells.
• I had studied about LR-asymmetric development by using Drosophila embryos.

• E and ID proteins regulate cell chirality and left–right asymmetric development in Drosophila
• Statistical Validation Verifies That Enantiomorphic States of Chiral Cells Are Determinant Dictating the Left- or Right-Handed Direction of the Hindgut Rotation in Drosophila
• Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin
• extra macrochaetae, encoding Drosophila Id, controls apical cell shape in the hindgut epithelium
• Chiral cell sliding drives left-right asymmetric organ twisting
• Cells with Broken Left–Right Symmetry: Roles of Intrinsic Cell Chirality in Left–Right Asymmetric Epithelial Morphogenesis
• The Drosophila AWP1 ortholog Doctor No regulates JAK/STAT signaling for left-right asymmetry in the gut by promoting receptor endocytosis

Post-embryonic development, caste differentiation, in termite

I had studied about the molecular mechanism of the caste differentiation in termites. Importantly, this is the developmental biology of the Superorganism.

• Plastic brain structure changes associated with the division of labour and ageing in termites
• Transgenerational epigenetic effect of kings’ aging on offspring’s caste fate mediated by sperm DNA methylation in termites
• A non-invasive method for sexing first and second instar larvae of termites using external morphology